butalbital will lower the level or outcome of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
Withdrawal indications can come about from conventional dosages and also just after shorter-phrase use, and may range between insomnia and stress to extra significant indications, like seizures and psychosis.
fentanyl intranasal and diazepam both improve sedation. Stay away from or Use Alternate Drug. Limit use to patients for whom different treatment method options are insufficient
fentanyl transmucosal and diazepam equally maximize sedation. Steer clear of or Use Alternate Drug. Restrict use to patients for whom option treatment method choices are insufficient
Calculations needs to be re-checked and should not be employed by itself to tutorial affected individual treatment, nor ought to they substitute for scientific judgment. See our entire disclaimer.
fosphenytoin will lower the extent or impact of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
diazepam increases toxicity of oliceridine by Other (see remark). Modify Therapy/Watch Closely. Comment: Anticholinergic medicines might maximize danger of urinary retention and/or critical constipation, which can lead to paralytic ileus.
Call your Health care supplier between visits as necessary, particularly if you happen to be concerned about symptoms. Suicidal thoughts or actions is often caused by things besides medicines. For those who have suicidal thoughts or steps, your Health care supplier might check for other triggers.
aprepitant will raise the degree or influence of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
cannabis will boost the degree or effect of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
lemborexant, diazepam. Either will increase outcomes of one other by sedation. Modify more info Therapy/Keep an eye on Carefully. Dosage adjustment could be essential if lemborexant is coadministered with other CNS depressants simply because of probably additive effects.
Adjunct use, if apprehension, panic or acute worry reactions existing just before endoscopic techniques
diltiazem will enhance the degree or outcome of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
apalutamide will lower the level or effect of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Coadministration of apalutamide, a robust CYP3A4 inducer, with medicines which are CYP3A4 substrates can result in decrease publicity to these prescription drugs.